土壤管理策略对病原体和环境抗体产生不同的影响
Colette A Nickodem1, Patricia Q Tran2,3, Eric Neeno-Eckwall4
1Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA. cnickodem@wisc.edu.
Scientific reports
|December 5, 2025
概括
有机农业实践,使用堆肥家禽便,增加了抗菌素耐药性 (AMR) 基因,但降低了它们的移动性. 非有机实践带来了更高的风险,因为AMR基因和人类病原体的移动性更高.
科学领域:
- 环境微生物学环境微生物学
- 农业科学 农业科学
- 基因组学就是基因组学.
背景情况:
- 抗微生物耐药性 (AMR) 基因是环境污染物,牲畜便是潜在的来源.
- 土壤管理在AMR基因持久性和肥料应用后传播中的作用尚不清楚.
研究的目的:
- 评估土壤管理实践如何影响土壤抗性和微生物群.
- 为了确定是否有机实践与堆肥家禽便增加AMR基因和病原体传播风险.
主要方法:
- 集成元基因组测序和风险评分分析的大规模实地实验.
- 评估ARG的丰富性,多样性和流动性,以及移动基因元素 (MGE).
主要成果:
- 非有机实践显示,由于ARG-MGE同时发生的增加,AMR基因和病原体传播的风险更高.
- 有机实践增加了ARG和金属耐药性基因 (MRG) 的总体丰度,但降低了它们的多样性和流动性.
结论:
- 仅仅关注ARG丰富性可能会误导AMR风险;基因流动性和管理环境至关重要.
- 土壤管理策略可以优化,以减轻AMR传播,支持可持续农业和公共卫生.
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