抑郁症状通过对衰老的态度影响脆弱:一个交叉滞后的分析
Bo Ye1, Yunxia Li2, Junling Gao3
1Shanghai Key Laboratory of Clinical Geriatric Medicine, Huadong Hospital, Fudan University, 168 West Yan'an Road, Shanghai, 200040, China. bo_ye@fudan.edu.cn.
BMC geriatrics
|December 5, 2025
概括
对衰老的积极态度 (AA) 可以减少老年人的抑郁症状 (DS) 和虚弱. 促进积极的AA可能有助于预防这两种情况,并提供了对它们相互联系的见解.
科学领域:
- 老年学是一门学科.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 在老年人中调查虚弱和抑郁症状 (DS) 之间的双向因果关系.
- 了解脆弱性与抑郁症联系背后的心理机制,特别是对衰老态度 (AA) 的作用.
- 解决关于AA如何调解脆弱性和DS之间的关系的知识差距.
研究的目的:
- 探索对老龄化态度 (AA) 在老年人脆弱和抑郁症状 (DS) 之间的相互关系中的调解作用.
- 检查脆弱性和DS之间的双向因果关系.
- 评估积极的AA对DS和脆弱的未来水平的影响.
主要方法:
- 一项基于社区的前性队列研究在上海,共有4082名60岁及以上的参与者.
- 使用经过验证的尺度评估脆弱性,DS和AA:中国脆弱性查尺度-10,患者健康问卷-9和对衰老的态度问卷-12.
- 应用交叉滞后模型来分析相互关系和调解效应.
主要成果:
- 在脆弱性和DS之间观察到显著的双向因果关系.
- 更大的脆弱性预测了更高的DS (β=0.142,P<0.001),更高的DS预测了更大的脆弱性 (β=0.058,P=0.006).
- 阳性AA显著预测了未来较低的DS (β=-0.051,P<0.001) 和脆弱性 (β=-0.055,P<0.001),AA调解了DS和脆弱性 (β=0.003,P=0.029) 之间的影响.
结论:
- 促进对衰老的积极态度 (AA) 对于预防老年人脆弱和抑郁症状 (DS) 至关重要.
- 在DS和脆弱性之间的关系中,AA扮演着重要的调解角色.
- 这些发现提供了对抑郁症和脆弱性联系的心理机制的宝贵见解,为有针对性的干预提供了信息.
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