自适应性伤口带用于伤口愈合和修复
Xin Zhao1, Huiru Xu1, Yuchen Sun1
1State Key Laboratory for Mechanical Behavior of Materials, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, China.
Advanced materials (Deerfield Beach, Fla.)
|December 6, 2025
概括
自适应性伤口带动态地响应伤口状况,不同于传统的伤口带. 这篇评论探讨了先进的材料和智能伤口护理的未来方向,改善愈合结果.
科学领域:
- 生物材料科学 生物材料科学
- 再生医学是一种再生医学.
- 伤口治愈研究研究 伤口治愈研究
背景情况:
- 皮肤对于防御和平衡至关重要,但慢性伤口面临着感染和炎症等挑战.
- 传统带提供被动保护,无法适应动态的伤口环境.
研究的目的:
- 提供对自适应性伤口带的全面审查.
- 为了比较传统和自我适应的方法,突出材料和功能上的进步.
- 讨论智能伤口护理方面的挑战和未来方向.
主要方法:
- 对皮肤修复,慢性伤口障碍和自适应包裹技术的文献综述.
- 对包括水凝,薄膜,海绵,微针,纳米纤维,生物传感器和纳米/微粒系统在内的平台进行批判性评估.
- 分析材料设计,结构工程和功能集成在先进的包装.
主要成果:
- 自适应带提供刺激反应,受控释放,机械适应性和生物活性,用于量身定制的伤口支.
- 像水凝和纳米纤维这样的各种平台在治疗急性,慢性和复杂伤口方面表现有前途.
- 关键的挑战包括生物安全性,可扩展性和临床翻译的个性化.
结论:
- 自适应性伤口包裹代表了与传统被动包裹相比的重大进步.
- 需要进一步的研究和开发,以克服临床翻译障碍,实现个性化的伤口治疗.
- 智能伤口护理系统有望改善各种伤口类型的愈合结果.
相关概念视频
Phases of Wound Repair
7.8K
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
7.8K
Clinical Applications of Epidermal Stem Cells
3.2K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.2K
Overview of Regeneration and Repair
5.0K
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
Regeneration
All animals have varying degrees of...
5.0K
Inflammatory Response II: Inflammatory Exudate and Tissue Repair
7.3K
The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
7.3K


