果用于预防尿路化 (APUL):一个随机交叉试验
Benjamin Baker1,2, Christine Herforth1,3, Josiah Low4
1Department of Urology, Naval Medical Center San Diego, 34800 Bob Wilson Dr, San Diego, CA, 92134, USA.
International urology and nephrology
|December 6, 2025
概括
果 (ACV) 没有通过改变尿中酸盐水平来显示石头预防作用. 然而,子水和水在非结石者中增加了尿中酸盐.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 预防结石是一个重要的临床问题.
- 尿酸在抑制结石形成方面起着至关重要的作用.
- 饮食干预措施正在探索它们在管理结石风险方面的潜力.
研究的目的:
- 调查果 (ACV) 补充剂对与预防结石相关的关键尿路参数的影响.
- 为了评估24小时尿中酸盐,pH和体积在ACV摄入后的变化.
主要方法:
- 进行了一项随机交叉试验,涉及非石材形成者.
- 参与者被指派每天饮用四种饮料之一 (ACV,子水,水,苏打) 一周,然后洗期和第二种饮料.
- 进行了三次24小时尿液采集:基线,第一次治疗后和第二次治疗后.
主要成果:
- 果 (ACV) 没有显著改变24小时的尿中酸盐,pH或体积.
- 子水摄入与尿中酸盐 (+273.8毫克/24小时) 的显著增加有关.
- 摄入水也显示尿中酸盐的显著增加 (+167.7毫克/24小时).
结论:
- 果似乎没有通过影响尿中酸盐水平来具有预防结石的特性.
- 子水和水在增加尿中酸盐方面表现出潜在的潜力,尿中酸盐是一种预防结石的保护因素.
- 需要进行更大的队列研究来证实这些发现及其临床影响.
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