在临床环境中暴露于生物气溶的风险:支气管镜检查
Noelia Gómez-Sánchez1, Lorena Alcalde2, José N Sancho-Chust3
1Department of Plant Production and Microbiology, Miguel Hernández University, San Juan de Alicante, Alicante, Spain; Institute for Sanitary and Biomedical Research of Alicante (ISABIAL), Alicante, Spain; Department of Applied Physics, Miguel Hernández University, Elche, Spain.
American journal of infection control
|December 6, 2025
概括
支气管检查会产生传染性气溶,对医疗保健工作者构成职业风险. 这项研究量化了在手术期间的生物气溶暴露,识别了包括SARS-CoV-2在内的细菌,真菌和病毒.
科学领域:
- 职业健康 职业健康 职业健康
- 传染病流行病学 传染病流行病学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 医疗保健专业人员面临职业感染的高风险.
- 像支气管镜术这样的程序可以产生含有微生物的气溶,增加感染风险.
- 在支气管镜检查期间量化生物气溶度对于评估职业暴露至关重要.
研究的目的:
- 在支气管镜检查期间量化生物气溶度.
- 评估医疗保健专业人员的职业感染风险.
- 为了识别支气管镜检查过程中产生的气溶中存在的微生物.
主要方法:
- 气溶样本是在例行支气管镜检查期间采集的,使用个人样本.
- 细菌和真菌殖民地分别使用16S rDNA和ITS1-2测序来确定.
- 使用RT-PCR检测出包括SARS-CoV-2在内的呼吸道病毒.
主要成果:
- 287个微生物殖民地从支气管镜检查期间采集的样本中分离出来.
- 丰富的细菌属包括微菌,葡萄球菌和细菌;真菌属包括阿斯伯吉卢斯,塔拉罗米塞斯和克拉多斯波里亚.
- 检测到潜在的致病物种和8个未被怀疑的SARS-CoV-2阳性样本,估计暴露量为98.94CFU/m3没有防护设备.
结论:
- 支气管镜能产生含有来自呼吸道的各种微生物的气溶.
- 这些气溶含有潜在的病原体,可以被医护人员吸入.
- 这些气溶的吸入对医疗保健专业人员造成职业感染的重大风险.
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