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Updated: Jan 9, 2026

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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STING-OLA1-Keap1-Nrf2轴调节过早卵巢衰竭中的铁亡

Nie Zhang1, Jiaoyu Li2, Ruixin Zhang3

  • 1Department of Obstetrics and Gynecology, NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, the First Affiliated Hospital of Anhui Medical University, No 218 Jixi Road, Hefei, 230022, Anhui, China; Department of Oncology, Fuyang Hospital of Anhui Medical University, Fuyang, 236000, China; Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, No 218 Jixi Road, Hefei, 230022, Anhui, China.

International journal of biological macromolecules
|December 6, 2025
PubMed
概括

干扰素基因 (STING) 途径的循环GMP-AMP合成酶 (cGAS) 刺激器驱动铁亡,导致早产卵巢衰竭 (POF) 中的粒状细胞损失. 抑制STING或使用Icariin (ICA) 可以保护卵巢储备.

关键词:
铁性化 (ferroptosis) 是一种过早的卵巢衰竭是早期的卵巢衰竭.刺痛是一种刺痛.

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