周围动脉疾病对膝下截肢患者的行走功能产生负面影响,有针对性的肌肉再生
Luke J Llaurado1, William J Zhu1, Kishan S Shah1
1Georgetown University School of Medicine, Washington, DC.
Annals of vascular surgery
|December 6, 2025
概括
周围动脉疾病 (PAD) 在接受下截肢 (BKA) 与向肌肉再内核 (TMR) 的患者中显著损害下肢功能. 这些人表现出较差的步行速度和稳定性,需要专门的康复方法.
科学领域:
- 整形外科 整形外科 整形外科
- 血管外科 血管外科
- 康复医学 康复医学 康复医学
背景情况:
- 周围动脉疾病 (PAD) 是与周围神经病变的常见并发症,增加截肢风险.
- 膝下截肢 (BKA) 显著影响患者的行动能力.
- 向肌肉再生 (TMR) 改善了手术结果,但功能挑战仍然存在,特别是在PAD.
研究的目的:
- 为了研究PAD对患有TMR的BKA患者下肢功能的影响.
- 为了比较PAD和非PAD患者之间的步态参数,后BKA与TMR.
主要方法:
- 一个单一中心的研究包括成人患者接受BKA与TMR.
- 在120秒的步行和30秒的罗姆伯格摇摆测试中,使用可穿戴传感器进行了步行分析.
- 测量和分析了包括速度,单肢/双肢支和步伐长度在内的关键步行参数.
主要成果:
- 在18名BKA和TMR患者中,10名患者 (55.6%) 患有PAD.
- 患有PAD的患者表现出明显减少的步行速度,单肢支和步伐长度 (P=0.01).
- 在PAD患者中,双肢支显著更高 (P=0.01),表明稳定性较差.
结论:
- 患有PAD,接受BKA和TMR的患者表现出明显的步行功能受损.
- 这些发现强调,需要针对BKA后的PAD患者制定定制的康复策略,以改善TMR的流动性.
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