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尤比基因特异蛋白酶5通过去除MAVS和IRF3的尤比基因,促进了EV-A71的复制

Shumin Zhang1, Yuan Fang2, Shuai Ren1

  • 1Joint National Laboratory for Antibody Drug Engineering, Henan University, Kaifeng 475004, China.

Virologica Sinica
|December 6, 2025
PubMed
概括

人类肠道病毒A71 (EV-A71) 通过升调全素特异蛋白酶5 (USP5) 来逃避免疫反应. 抑制USP5可以增强抗病毒信号传输,为抗手足口病提供新的治疗策略.

关键词:
肠道病毒A71 (EV-A71) 是一种病毒.这是天生的免疫力.干扰素调节因子3 (IRF3)线粒体抗病毒信号蛋白 (MAVS)乌比基特异性蛋白酶5 (USP5) 是一种

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