印度对 Paroxysmal 和持久性心房动进行冷移除的经验
Sudipta Mondal1, Nayani Makkar1, Usnish Adhikari1
1Department of Cardiology, Electrophysiology Division, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, PIN 695011, India.
Indian pacing and electrophysiology journal
|December 6, 2025
概括
在亚洲,冷热气球除对于心房动 (AF) 是安全有效的. Paroxysmal AF (PAF) 的成功率高于持久性AF (PsAF),严重不良事件较少.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 关于亚洲的冷化结果的数据有限.
- 在西方人群中,冷可用于心房动 (AF).
- 这项研究解决了在非西方队列中了解冷移除疗效和安全性的差距.
研究的目的:
- 评估冷气球除在患有偏激性心房动 (PAF) 和持续性心房动 (PsAF) 的患者的安全性和疗效.
- 为了评估心房律乱复发和手术相关不良事件的自由.
- 为了比较PAF和PsAF受冷处理的患者之间的结果.
主要方法:
- 对66名患有复发性症状性AF的患者进行了回顾性观察性研究.
- 患者接受了冷却气球导管切除,以控制节律.
- 主要终点包括无AF/AFL/AT (≥30s) 在15.3个月的随访和30天内的严重不良事件.
主要成果:
- 总体而言,12个月内心脏不律的自由率为71%,在PAF (84%) 与PsAF (34%) 相比,PAF显著更高.
- 发生了两个严重的不良事件 (3.03%) (神经损伤),在3个月内消失.
- 需要心脏转换的手术前和手术后心律失常与更高的复发风险有关.
结论:
- 在这个队列中,冷热气球除对治疗PAF和PsAF有效且安全.
- 在PsAF中更高的复发率强调了需要量身定制的治疗策略.
- 不良事件的发生率与全球标准相比较,支持其在亚洲的使用.
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