在储存期间从婴儿配方奶粉中提取的细胞外囊泡的特征和脂质学:从味道恶化的洞察力
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Updated: Jan 9, 2026

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Evaluation of the Storage Stability of Extracellular Vesicles
Published on: May 22, 2019
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Jianfeng Wang1, Jiarun Xu2, Lunaike Zhao1
1Key Laboratory of Geriatric Nutrition and Health, Ministry of Education, Beijing Technology & Business University, Beijing 100048, China.
Food research international (Ottawa, Ont.)
|December 6, 2025
概括
婴儿配方奶粉中的细胞外囊泡 (EVs) 在储存期间发生变化,影响味道. 在IF衍生的EV (IFEV) 中的脂质变化与异味相关,为质量改进提供了洞察力.
科学领域:
- 乳制品科学 乳制品科学
- 利皮多米克 (Lipidomics) 是一种消化剂.
- 细胞外囊泡生物学 细胞外囊泡生物学
背景情况:
- 牛奶衍生的细胞外囊泡 (EVs) 含有生物活性分子.
- 在储存过程中对婴儿配方 (IF) 衍生 EVs (IFEVs) 及其与风味的联系的了解有限.
- EV脂质变化与食品质量恶化有关.
研究的目的:
- 为了研究储存期间IFEVs的变化.
- 探索IFEV脂质配置和风味恶化之间的关系.
- 为了识别关键的脂质和涉及脱口味形成的途径.
主要方法:
- 使用梯度超离心法隔离IFEV.
- 通过纳米颗粒追踪分析,电子显微镜,西部斑块和非向脂质组学进行表征.
- 相关性分析和加权脂质共同表达网络分析,以将脂质变化与风味生物标志物联系起来.
主要成果:
- 在成分上,IFEV与原牛奶衍生的EV (RMEV) 不同.
- 储存时间显著改变了IFEV脂质谱.
- 特定的脂质转移与异味相关,涉及到甘油脂代谢.
结论:
- IFEV的脂质变化与储存期间婴儿配方奶粉脱口味的发展有关.
- 甘油脂代谢是调解这些风味变化的关键途径.
- 结果可以指导优化IF存储和提高产品质量的策略.
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