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在瘤胰腺和肝脏手术后的静脉血栓塞栓症
Kelly Dong1, Ashlynn Fuccello2, Mario Schootman2
1Department of Surgery, McMaster University, Hamilton, Ontario, Canada; Bloomberg School of Public Health, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
概括
静脉血栓栓塞 (VTE) 是肝脏或胰腺手术后的一种风险. 诸如女性性别,较高的风险分数和晚期癌症等因素增加了术后六个月内静脉瘤的发展.
科学领域:
- 在瘤学瘤学.
- 血管外科 血管外科
- 流行病学 流行病学
背景情况:
- 静脉血栓塞栓症 (VTE) 在肝胆瘤手术后具有显著的风险.
- 了解VTE发生率和时间对于患者的治疗结果至关重要.
研究的目的:
- 为了调查胰腺和肝癌手术后VTE事件的发生率和时间.
- 为了确定与VTE发展相关的临床和社会人口因素.
主要方法:
- 对SEER-Medicare数据库 (2002-2019) 的分析.
- 包括接受切除的原发性胰腺或肝癌患者.
- 主要结局:VTE在90天内;次要结局:DVT,PE和晚期VTE (91-180天).
主要成果:
- 在17756名患者中,10%的患者在手术后六个月内发展出静脉瘤.
- 静脉瘤发作事件发生在术后1个月 (32%) 和3个月 (67%) 之内.
- 独立的VTE预测因素包括女性性别,更高的风险得分,城市居住,医疗补助资格,晚期,惠普尔手术和较低的医院体积.
结论:
- 在胰腺和肝癌手术后,VTE事件持续长达六个月.
- 确定了临床和社会人口因素,使VTE风险分层能够改善患者管理.
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