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Updated: Jan 9, 2026

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
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一个JAK/STAT-Pdk1-S6K轴绕过系统生长限制以促进再生

Ananthakrishnan Vijayakumar Maya1,2,3, Lena Neuhaus4,5,6, Liyne Nogay1,2,3

  • 1Hilde-Mangold-Haus, University of Freiburg, Freiburg, Germany.

Nature communications
|December 6, 2025
PubMed
概括

炎症引起的组织损伤导致系统性生长限制. 再生细胞通过JAK/STAT通路通过Pdk1 (酸氨基醇依赖激酶-1) 的上调来克服这一问题,从而使增殖成为可能.

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