中央和外围因素缓和疼痛影响运动控制和残疾的慢性腰椎神经根性疼痛
Roya Khanmohammadi1, Soheila Qanbari2, Hanie Sadat Hejazi2
1Iranian Center of Excellence in Physiotherapy, Rehabilitation Research Center, Department of Physiotherapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran. rkhanmohammadi@sina.tums.ac.ir.
Journal of neuroengineering and rehabilitation
|December 6, 2025
概括
皮层刺激性和干部肌肉活动影响疼痛强度和持续时间如何影响慢性腰椎神经根部疼痛中的残疾和运动控制. 增强的中心和外围因素与更好的结果有关.
科学领域:
- 神经科学是一个神经科学.
- 生物医学工程 生物医学工程
- 康复科学 康复科学 康复科学
背景情况:
- 运动控制涉及从感觉运动皮质到外围肌肉的等级系统.
- 预期性 (APA) 和补偿性 (CPA) 姿势调整是与中心过程相互作用的关键外围机制.
- 这些相互作用对于保持运动控制和姿势稳定至关重要.
研究的目的:
- 为了确定皮层刺激性和深层干部肌肉活动是否能缓和慢性腰椎神经根部疼痛中疼痛特征和功能结果之间的联系.
- 具体来说,要检查在APA/CPA阶段的感觉唤起潜能 (SEPs),运动唤起潜能 (MEPs) 和干肌电肌图 (EMG) 的作用.
主要方法:
- 一项对44名患有慢性单侧腰部神经根部疼痛的参与者的横截面研究.
- 使用PROCESS (模型1) 评估的预测因子 (疼痛强度/持续时间),结果 (残疾/运动控制) 和调节因子 (皮层/肌肉测量) 的调节分析.
- 年龄受到控制,条件效应估计在特定百分点.
主要成果:
- 在APA期间感官皮层刺激性 (N150) 和侧腹肌活动对残疾的缓解疼痛强度的影响.
- 感官皮层刺激性 (N80) 和腹部APA活动减弱了疼痛持续时间和残疾相关性.
- 反侧腹部APA活动对运动控制结果产生了边际影响.
结论:
- lumbosacral 根部疼痛的功能结果是由中央和外围因素的结合形成的.
- 增强的皮层刺激性和两侧腹肌活动与缓解疼痛-残疾关系和更好的运动控制相关.
- 另一方的APA活动也可能影响运动控制,尽管其影响不那么明显.
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