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在COVID-19感染后食道运动障碍
Žarko Babić1,2, Leo Bezdrov3, Vesna Eraković Haber4,5
1Department of Medicine, Division of Gastroenterology, Dubrava University Hospital, Av. Gojka Šuška 6, Zagreb, Croatia. zarko.babic@zg.t-com.hr.
在以前没有有效的食道运动的患者中,COVID-19感染可能会使食道运动问题恶化. SARS-CoV-2可能会对食道功能产生负面影响,导致长时间的远端延迟和感染后收缩速度降低.
科学领域:
- 胃肠病学 胃肠病学
- 食道运动障碍 食道运动障碍
- 传染病并发症 传染病并发症
背景情况:
- 众所周知,COVID-19 (冠状病毒疾病2019) 会影响多个器官.
- 感染后的后续症状,包括胃肠道表现,越来越多地被认可.
- 食道动力不良可以出现诸如消化不良和胸部不适之类的症状.
研究的目的:
- 为了调查COVID-19感染后食道测量参数的变化.
- 评估SARS-CoV-2 (严重急性呼吸系统综合征-2) 对先前存在无效食道运动的患者的影响.
- 为了评估COVID-19后的食道功能变化.
主要方法:
- 在COVID-19后恢复的84名患者中进行了高分辨率食道测量.
- 在SARS-CoV-2感染之前,患者已经被诊断出无效的食道运动.
- 结果与感染前的测量数据进行了比较;使用了芝加哥4.0分类.
主要成果:
- 收缩前速度 (CFV) 和远程收缩积分的显著减少被观察到.
- 检测到远端延迟的延长和周围静脉断裂大小的增加.
- 在快速吞后发现了SARS-CoV-2感染对远端收缩整体的显著影响.
结论:
- SARS-CoV-2 感染似乎对食道运动有负面影响.
- 在患有先前存在的疾病的患者中,食道动力障碍的恶化是一个显著的发现.
- 需要进一步的研究来了解这些COVID-19后食道变化背后的机制.
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