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开发和评估多式超声波放射学模型,用于预测类风湿性关节炎的活性炎症

Haiyan Tian¹, Jie Liu², Shigang Li³

¹Department of Ultrasound, The First College of Clinical Medical Science, China Three Gorges University, Yichang Central People's Hospital, No. 2 Jiefang Road, Xiling District, Yichang, Hubei, China.

Skeletal radiology

|December 6, 2025

概括

一个新的多式超声波放射学模型整合功率多普勒 (PD) 和卓越的微血管成像 (SMI) 显示在预测类风湿性关节炎 (RA) 中活跃炎症的高准确性. 这种方法提高了RA患者的诊断能力.

科学领域:

类风湿病学类风湿病学
医疗成像医学成像
无线电学 (Radiomics) 是一种放射学.

背景情况:

风湿性关节炎 (RA) 的诊断和监测依赖于对关节炎症的准确评估.
像功率多普勒 (PD) 和卓越的微血管成像 (SMI) 这样的超声波技术提供了对血管性的洞察,这是炎症的标志物.

研究的目的:

开发和评估一种多式超声波放射学模型,用于预测类风湿性关节炎 (RA) 中的活性炎症.
将功率多普勒 (PD) 和卓越的微血管成像 (SMI) 数据与临床因素相结合,以提高预测性能.

主要方法:

收集了2,503个PD和2,503个SMI超声波图像,这些超声波图像来自具有活跃炎症和对照的RA患者.
开发了单模式 (PD/SMI),多模式 (SMI_PD) 和临床集成的放射学模型.
使用接收器操作特征 (ROC) 分析评估诊断性能.

主要成果:

多式联网SMI_PD模型实现了曲线下的面积 (AUC) 为0.82.
临床综合模型显示最高的AUC为0.83.
单种模式的模型显示较低的AUC (PD:0.76,SMI:0.75).

结论:

多模式超声波放射学模型在预测RA活性炎症方面显著优于单模式方法.
卓越的微血管成像 (SMI) 显示出监测亚临床炎症的前景.
将多式超声波放射学与临床数据相结合,提高了类风湿性关节炎的诊断效用.

关键词:

活动性炎症活动性炎症多式超声波多式超声波类风湿性关节炎类风湿性关节炎类风湿性关节炎超声波的辐射学.

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