[针对免疫功能低下的成年患者的疫苗接种建议]
Cândida Abreu1, Susana Peres2, Flávia Cunha3
1Serviço de Doenças Infeciosas. Unidade Local de Saúde São João. Porto. Portugal; RISE-Health. Departamento de Medicina. Faculdade de Medicina. Universidade do Porto. Porto. Portugal.
Acta medica portuguesa
|December 7, 2025
概括
疫苗接种对于免疫力低下的成年人至关重要,因为他们感染感染的风险增加. 根据个体免疫抑制水平和时间调整疫苗接种计划是最佳保护的关键.
科学领域:
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
- 疫苗学 疫苗学 疫苗学
背景情况:
- 免疫功能低下的成年人面临疫苗可预防疾病的风险增加.
- 与免疫能力强的人相比,他们对疫苗的免疫反应可能会减弱.
- 当可能时,评估疫苗反应至关重要.
研究的目的:
- 巩固针对免疫功能低下的成年人的国际疫苗接种指南.
- 强调基于免疫抑制状态的个性化疫苗接种策略.
- 为了指导最佳的疫苗时间和选择.
主要方法:
- 审查国际领先卫生机构的建议.
- 免疫受损个体的分类 (例如,炎症性疾病,移植受体,艾滋病毒,先天性免疫缺陷).
- 对疫苗的指示,风险,禁忌和时间进行分析.
主要成果:
- 针对各种临床情景和免疫抑制类型,提供了具体的疫苗推.
- 讨论的主要疫苗包括流感疫苗,COVID-19,RSV,甲型/乙型肝炎,天花,肺炎球菌,脑膜炎球菌和Haemophilus influenzae.
- 在免疫抑制疗法,脊髓切除术或移植之前优先接种疫苗.
结论:
- 疫苗接种策略必须根据个体的免疫抑制状态进行调整.
- 接种家庭接触者和医疗保健专业人员的疫苗可以提高保护.
- 由于疫苗的进步,需要不断更新指南.
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