相关实验视频

Updated: Jan 9, 2026

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

埃普斯坦-巴尔病毒传染性单核病中的血小板缺血和中性缺血:一项回顾性队列研究

Patrick Naughton¹, James V Harte², Brigid Lucey³

¹Department of Biological Sciences, Munster Technological University, Rossa Avenue, Bishopstown, Cork, Ireland; Department of Haematology, Mercy University Hospital, Grenville Place, Cork, Ireland.

Biomolecules & biomedicine

|December 7, 2025

概括

研究了埃普斯坦-巴尔病毒传染性单核病 (EBV-IM) 中常见的血小板减少和绝对中性质减退. 这些血清变化也出现在其他病毒感染中,而不仅仅是急性EBV-IM.

科学领域:

血液学血液学血液学
病毒学病毒学
传染性疾病传染性疾病

背景情况:

血小板缺血和绝对中性质缺血是已知的埃普斯坦-巴尔病毒传染性单核病 (EBV-IM) 的并发症.
在EBV-IM中这些血液学异常的患病率和诊断意义需要进一步澄清.

研究的目的:

确定怀疑EBV-IM的患者中血小板缺血和绝对中性质缺血的患病率.
为了比较这些血液学发现在急性EBV-IM与非急性EBV-IM病例中的发生率,有和没有异型淋巴细胞.

主要方法:

从2018-2019年间对EBV-IM进行测试的患者的实验室结果的回顾性分析.
包括51个已确认的急性EBV-IM病例.
在急性EBV-IM,非急性EBV-IM与异型淋巴细胞之间以及非急性EBV-IM没有异型淋巴细胞之间的血液学并发症率的比较.

主要成果:

在51例确诊的急性EBV-IM病例中,有14%出现了血小板缺血和绝对中性质缺血,包括严重病例.
在非急性EBV-IM患有异型淋巴细胞的患者中观察到这些疾病的类似患病率.
在没有异型淋巴细胞的非急性EBV-IM患者中发现血小板缺血和绝对中性质缺血的发生率明显较低.

结论:

血小板缺血和绝对中性质缺血并不仅限于急性EBV-IM.
这些血液学异常可能发生在各种病毒感染中.
在非急性EBV-IM病例中,异型淋巴细胞的存在可能表明这些血清变化的风险更高.

更多相关视频

An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection

An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection

Published on: March 30, 2018

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line

Isolation and Quantification of Epstein-Barr Virus from the P3HR1 Cell Line

Published on: September 28, 2022

相关概念视频

Immunodeficiency Diseases

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...

Disorders of Leukocytes

Disorders of Leukocytes

Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...