细分/多焦点发作是异常成年发作 dystonia 的一个独特的表现吗?
Vittorio Velucci1, Carmen Terranova2, Francesco Bono3
1Department of Translational Biomedicine and Neuroscience, University of Bari Aldo Moro, Bari, Italy.
异常成年发病性 dystonia (IAOD) 可以呈现为焦点或分段/多焦点发病. 这项研究发现发病类型之间没有显著差异,这表明细分/多焦发病是IAOD的有效表现.
科学领域:
- 神经学 神经学
- 运动障碍 运动障碍
背景情况:
- 异常成年发病性 dystonia (IAOD) 通常被认为是焦点的,但已有细分/多焦点发病的报道.
- 细分/多焦点发病的起源 (真实呈现与回忆偏差) 仍然不清楚.
研究的目的:
- 调查细分/多焦点发作是否是一种独特的IAOD呈现.
- 将细分/多焦点发病的患者与焦点发病的患者进行比较.
主要方法:
- 来自意大利 dystonia 登记册的 863 位 IAOD 患者的 dystonia 身体分布的分析.
- 包括在症状出现一年内评估的患者,以最大限度地减少回忆偏差.
主要成果:
- 细分或多焦点发作发生在10%的病例中.
- 发病类型与性别,年龄,家族病史,甲状腺疾病或疾病传播无关.
- 不管评估时间如何,细分/多焦点发病的比例保持稳定,反驳了回忆偏差.
结论:
- 细分/多焦点发作是IAOD的有效表现,不能归因于回忆偏差.
- 细分/多焦点发病的患者与焦点发病病例具有相似的特征.
- 结果可能会为IAOD患者的预后咨询提供信息.
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