在酸盐/酸盐微囊中封装后,增强了富含赫斯佩里丁的血提取物的生物可访问性
Thais Fernanda de Marco1, Luana Bettanin2, Liciani Inaê Putti1
1Santa Catarina State University, Postgraduate Program in Food Science and Technology, Br 282, km 574, 89870-000, Pinhalzinho, /SC, Brazil.
Food chemistry
|December 7, 2025
概括
将血提取物封装在酸盐/酸盐微囊中可以提高hesperidin的生物可访问性和稳定性. 这种方法显示了功能性食品的潜力,其目标是食后血糖控制.
科学领域:
- 食品科学 食品科学 食品科学
- 营养生物化学 营养生物化学
- 材料科学 材料科学 材料科学
背景情况:
- 血提取物含有具有抗氧化和血糖控制特性的生物活性化合物.
- 赫斯佩里丁是一种关键的黄类化合物,其生物可用性和稳定性有限.
- 封装是一种提高生物活性化合物输送的策略.
研究的目的:
- 通过离子凝使用阿尔金酸盐/奇托桑来封装血果肉提取物.
- 评估封装对西的生物可访问性和稳定性的影响.
- 评估封装提取物对食后血糖控制的潜力.
主要方法:
- 离子凝使用阿尔金酸盐/奇托桑进行微封装.
- 使用分析方法量化hesperidin的量化.
- 在体外抗氧化活性测定 (FRAP,ABTS,ORAC).
- 对肠道分糖酶 (糖酶) 的抑制试验.
- 模拟消化以评估胃保护和生物可访问性.
主要成果:
- 赫斯佩里丁的封装效率为70.07%.
- 封装 hesperidin 在生物可访问性指数 (2.96 至 26.2) 中显著增加.
- 提取物显示出强烈的抗氧化活性和55.9%的糖酶抑制.
- 微囊对胃部降解提供了显著的保护.
结论:
- 酸盐/花酸盐封装有效地提高了hesperidin的稳定性和生物可访问性.
- 封装的血提取物对功能性食物和血糖管理有希望.
- 该战略支持开发促进健康的产品,以改善素的输送.
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