相关实验视频

Updated: Jul 9, 2026

Primary Microglia Isolation from Mixed Glial Cell Cultures of Neonatal Rat Brain Tissue
10:20

Primary Microglia Isolation from Mixed Glial Cell Cultures of Neonatal Rat Brain Tissue

Published on: August 15, 2012

40.5K

在脊髓损伤中,NNT通过线粒体氧化应激抑制微质激活

Ming Li1, Qiuyue Gu2, Zhenyu Fan3

  • 1Department of Spine Surgery, Affiliated Hospital of Nantong University, 226001 Nantong, Jiangsu, China.

Neuroscience letters
|December 7, 2025
PubMed
概括

尼古丁胺核酸转酶 (NNT) 通过减少线粒体氧化应激来抑制脊髓损伤 (SCI) 炎症. 在小鼠中过度表达NNT改善了SCI后的功能恢复,突出了其治疗潜力.

关键词:
炎症 炎症是一种炎症.微质激活的作用NNT NNT 是一个字母.氧化应激是一种氧化应激.脊髓损伤导致的脊髓损伤

更多相关视频

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates09:12

Isolation of Cortical Microglia with Preserved Immunophenotype and Functionality From Murine Neonates

Published on: January 30, 2014

16.6K
Identifying Microglia and Peripheral Infiltrating Macrophages in the Injured Spinal Cords Using Flow Cytometry08:47

Identifying Microglia and Peripheral Infiltrating Macrophages in the Injured Spinal Cords Using Flow Cytometry

Published on: June 24, 2025

622

相关概念视频

Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...