由Streptococcus pyogenes的Shr蛋白结合的结构基础

Kanta Seki1, Akinobu Senoo1, Satoru Nagatoishi2

  • 1Laboratory of Protein Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.

概括

这项研究揭示了Streptococcus pyogenes中关键的血结合域的晶体结构,识别了铁获取至关重要的氨酸残留物. 这些发现为打击抗生素耐药性细菌感染提供了新的目标.

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