相关实验视频

Updated: Jan 9, 2026

Accessing the Cytotoxicity and Cell Response to Biomaterials

Accessing the Cytotoxicity and Cell Response to Biomaterials

Published on: July 8, 2021

用于牙损伤的牙上应用的基于黄素的原料对纸细胞的跨牙效应

Beatriz Ometto Sahadi^1,2, Igor Paulino Mendes Soares^2,3, Chloe Gifford²

¹Department of Restorative Dentistry, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil.

Clinical oral investigations

|December 7, 2025

概括

应用于病影响的牙上的黄类原料对纸细胞是安全的,并促进矿物化. 这些化合物降低了氧化应激,在牙科治疗期间支持纤维的健康.

科学领域:

生物材料科学生物材料科学
牙纸生物学牙纸生物学
细胞生物学细胞生物学

背景情况:

牙损伤的牙需要保守的管理,以保持纸的活力.
在牙预处理过程中,脉刺激是一种风险.
黄酸是具有潜在治疗性能的天然化合物.

研究的目的:

评估牙纸细胞和巨细胞对虫影响牙上的基于黄类原料的生物反应.
评估黄酸原料原料对细胞活力,矿化和氧化应激的影响.

主要方法:

制备了类原料 (Naringin,Kaempferol,Baicalein) 并应用于牙受损伤的牙盘.
在初级应用后,评估了质细胞样细胞 (MDPC-23) 的细胞活力和形态.
经牙扩散提取物在牙髓干细胞 (DPSC),MDPC-23和巨细胞 (RAW 264.7) 上进行了活力,矿化和反应性氧物种 (ROS) 生产的测试.

主要成果:

黄类原料并没有降低MDPC-23细胞活力.
原始剂略微提高了DPSC活力,并在7天内保持了MDPC-23活力.
黄酸的应用促进了矿化,并减少了巨细胞中ROS的产生.

结论:

基于黄类的原料对纸细胞无细胞毒性.
这些原料刺激矿化,减少氧化应激,表明对纸组织有保护作用.
黄酸原料原料代表了一种有前途的保守策略,用于管理牙受损的牙,并最大限度地减少肉刺激.

关键词:

牙腐烂是指牙的腐烂.牙上的牙.黄类化合物黄类化合物它们是Odontoblasts.有毒性有毒性

更多相关视频

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites

Published on: November 9, 2014

相关概念视频

Tooth Anatomy

Tooth Anatomy

The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...