度 (mosmol/kg H2O) 与度 (mosmol/L):应用生理学,以提高患者的安全性
Rolf Zander1, Thomas Ziegenfuß2, Robert Sümpelmann3
1Physioklin, formerly Institute of Physiology and Pathophysiology, University Medical Center, Mainz, Germany.
European journal of medical research
|December 7, 2025
概括
度在临床医学中至关重要,以防止患者受到伤害. 了解度并正确使用它,而不是度,有助于避免危险的流体移动,并指导适当治疗电解质失衡.
科学领域:
- 临床医学 临床医学
- 生理学 生理学 生理学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 透压力失衡可能导致患者的严重发病率和死亡率.
- 度是一个关键的临床参数,但它的解释往往不准确.
- 了解度的生理基础对于预防住院患者的并发症至关重要.
研究的目的:
- 审查度的生理背景,以改善临床理解.
- 预防住院患者与度失衡相关的并发症.
- 建议在临床环境中测量和解释度的最佳实践.
主要方法:
- 对控制度的生理原理的审查.
- 对临床实践的分析与度的测量和解释.
- 度 (mosmol/kg H2O) 与度 (mosmol/L) 的比较.
主要成果:
- 为准确的临床评估,建议使用度 (mosmol/kg H2O) 与度 (mosmol/L) 相比,特别是当比较含水量不同的溶液时.
- 细胞外液体或血替代的静脉注射液应是同位素的 (280300莫斯摩尔/千克H2O),以防止不必要的水位转移.
- 低度通常与低度有关;最近的证据表明,更慢的校正率与死亡率的增加有关.
结论:
- 准确的临床测量和解释度对于患者的安全至关重要.
- 制造商和临床医生对度的报告进行标准化是必要的.
- 适当管理度,特别是在低度的情况下,对于改善患者的治疗结果至关重要.
更多相关视频
06:07Osmotic Pump-based Drug-delivery for In Vivo Remyelination Research on the Central Nervous System
Published on: December 17, 2021
5.8K
14:28Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care
Published on: May 10, 2024
2.1K
相关概念视频
Osmosis and Osmotic Pressure of Solutions
45.7K
A number of natural and synthetic materials exhibit selective permeation, meaning that only molecules or ions of a certain size, shape, polarity, charge, and so forth, are capable of passing through (permeating) the material. Biological cell membranes provide elegant examples of selective permeation in nature, while dialysis tubing used to remove metabolic wastes from blood is a more simplistic technological example. Regardless of how they may be fabricated, these materials are generally...
45.7K
Osmosis
192.3K
Approximately 60% to 95% of the weight of living organisms is attributed to water. Therefore, maintaining appropriate water balance within cells is of paramount importance. Osmosis is the movement of water across a semipermeable membrane, such as a cell’s plasma membrane. In living organisms, water plays a crucial role as a solvent—a molecule that dissolves other molecules.
192.3K
Osmosis
10.3K
Osmosis is the movement of free water molecules through a semipermeable membrane. The water's concentration gradient across the membrane is inversely proportional to the solutes' concentration. Whereas diffusion transports material across membranes and within cells, osmosis transports only water across a membrane, and the membrane limits the diffusion of solutes in the water. Osmosis is a special case of diffusion.
Water, like other substances, moves from a high concentration of...
Water, like other substances, moves from a high concentration of...
10.3K
Factors Influencing Microbial Growth: Osmolarity
695
Osmolarity is the measure of solute concentration in a solution. It plays a critical role in determining water availability for organisms. Water moves across semipermeable membranes through osmosis, flowing from regions of lower solute concentration (more dilute) to regions of higher solute concentration (more concentrated).In high-solute environments, microbial cells lose water, leading to dehydration and inhibited growth. The extent to which water is available to microbes in such environments...
695
Regulation of Water Intake
2.6K
Osmolality refers to the number of solute particles per kilogram of solvent in a solution. Plasma osmolality specifically indicates the total number of solute particles per kilogram of water in blood plasma. This value reflects the body's hydration status and is tightly regulated through mechanisms controlling water intake and output. While water consumption is a conscious decision, the body has intrinsic regulatory systems to maintain fluid balance. Dehydration, a state of water deficit...
2.6K
Tonicity in Animals
123.2K
The tonicity of a solution determines if a cell gains or loses water in that solution. The tonicity depends on the permeability of the cell membrane for different solutes and the concentration of nonpenetrating solutes in the solution within and outside of the cell. If a semipermeable membrane hinders the passage of some solutes but allows water to follow its concentration gradient, water moves from the side with low osmolarity (i.e., less solute) to the side with higher osmolarity (i.e.,...
123.2K
