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系统性关联与迹象,症状及其不一致性在一个印度人口与干眼疾病的干眼疾病

Soumen Sadhu¹, Geetha Iyer, Janani Surya

¹Dr G Sitalakshmi Memorial Clinic for Ocular Surface Disorders (S.S., G.I., S.A., B.S.), CJ Shah Cornea Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India; and Medical Research Foundation (J.S.), Sankara Nethralaya, Chennai, India.

Eye & contact lens

|December 8, 2025

概括

系统性疾病显著影响干眼病 (DED) 的表现,有时会导致症状和症状之间的不匹配. 完整的患者病史对于有效的DED管理至关重要.

科学领域:

眼科医生眼科眼科
系统健康系统健康
临床研究临床研究

背景情况:

干眼病 (DED) 是一种普遍的疾病,具有多因素的原因.
系统性疾病与DED的临床表现之间的关系需要进一步阐明.
了解DED的症状-征兆不一致性对于准确的诊断和管理至关重要.

研究的目的:

调查与干眼病 (DED) 相关的系统性疾病的症状,征兆和症状-征兆不一致.
分析各种系统因素对被诊断的队列中DED呈现的影响.

主要方法:

对371名临床诊断的DED参与者的前性横截面研究.
系统性疾病通过自我报告,病历和专家推来评估.
用线性回归分析了DED症状和标志得分,以分析与系统性疾病的关联.

主要成果:

在DED的迹象和症状之间没有发现显著的相关性 (Spearman rho = -0.08;P=0.08).
年龄和DED持续时间与比症状更强的征兆相关.
亚托皮,胃肠道疾病,心理障碍和HRT使用与更严重的DED症状相联系.
女性性别,GVHD,Sjögren病和RA与更严重的DED症状和症状标志不一致有关.

结论:

系统性疾病显著影响DED表现,并可能导致症状与征兆不匹配.
识别相关的系统性疾病对于全面的DED评估至关重要.
临床实践应包括对DED患者进行彻底的全身病史检查.

关键词:

干眼疾病是干眼的疾病.干眼的症状和迹象干眼症状症状标志不和系统健康系统健康

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