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长期结果和结节复发的预后比较,用于持久和复发的分化甲状腺癌

Yung Jee Kang^1,2, Ji-Hoon Kim³, Ji Ye Lee³

¹Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.

Clinical and experimental otorhinolaryngology

|December 8, 2025

概括

复发的分化甲状腺癌 (DTC) 与持久的DTC相比,显示出较差的无疾病生存率 (DFS). 然而,复发性和持续性DTC患者的整体存活率 (OS) 仍然相似.

科学领域:

在瘤学瘤学.
手术瘤学手术瘤学
内分泌学在内分泌学.

背景情况:

差异化甲状腺癌 (DTC) 通常具有有利的预后.
由于常见的不确定的淋巴结发现,区分复发性和持续性DTC具有挑战性.
有限的研究存在于复发与持久DTC的比较预后.

研究的目的:

为了比较复发性与持续性DTC的预后和瘤特征.
在这些患者群体中确定影响无病生存 (DFS) 和整体生存 (OS) 的因素.

主要方法:

对265名因DTC而重新手术的患者进行了回顾性队列研究.
在初始诊断时排除患有远程转移的患者.
复发性和持续性DTC组之间的临床特征,淋巴结转移模式,DFS和OS的比较.

主要成果:

复发性DTC显示了更高的中央淋巴结转移率,内部复发率和远程转移率.
持久的DTC表现出更多的横向淋巴结转移和外场复发.
十年DFS的复发性DTC (41.0%) 显著低于持久性DTC (67.9%).
复发性DTC,年龄较大,转移性淋巴结数量较高和不完全切除与DFS降低有关.
两组之间没有观察到总生存时间 (OS) 的显著差异.

结论:

与持续性DTC相比,复发性DTC与明显较差的无疾病生存率有关.
在复发性和持续性DTC患者之间,整体存活率没有显著差异.

关键词:

没有疾病的生存率.淋巴细胞转移的转移.复发情况复发情况幸存率幸存率是指生存率.甲状腺新生瘤的发生.

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