在机械通风犬中比较SpO2/FiO2和PaO2/FiO2的比率
Gabriela L Rivas1,2, Jiwoong Her3,4, Deborah A Keys5
1Department of Small Animal Clinical Sciences, Texas A&M School of Veterinary Medicine & Biomedical Sciences, College Station, Texas, USA.
概括
在机械通风犬中,SpO2/FiO2 (SF) 比率与PaO2/FiO2 (PF) 比率有很强的相关性. SF可能是一个可靠的,非侵入性替代PF评估氧化,虽然动脉血液气体分析仍然是黄金标准.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 关键的护理关键的护理
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 评估机械通风犬的氧化率对于患者管理至关重要.
- PaO2 / FiO2 (PF) 比率是标准测量,但需要进行侵入性动脉血液采样.
- 在兽医重症监护中,对氧化评估的非侵入性方法是理想的.
研究的目的:
- 在机械通风犬中评估非侵入性SpO2/FiO2 (SF) 比率与侵入性PF比率之间的相关性.
- 要确定SF比率是否可以可靠地估计该患者群体中的PF比率.
主要方法:
- 一项前性,多中心的观察性研究,涉及37只需要机械通风的客户拥有的狗.
- 同时记录SpO2,FiO2和动脉血液气体值 (PaO2).
- 使用线性混合模型计算SF和PF比率并对它们的相关性进行统计分析.
主要成果:
- 在SF和PF比率之间发现了强烈的正相关性 (斯皮尔曼系数 = 0.70,p < 0.0001).
- 一个线性混合模型证明了一个可预测的关系:SF = 0.50 * (PF) + 103.
- 该SF比率显示足以突出能力预测PF值低于100,200和300的足够能力.
结论:
- 在机械通风犬中,SF比率是PF比率的强相关且潜在可靠的非侵入性替代品.
- 建立的线性模型允许根据SF值估计PF比率.
- 虽然SF表现有希望,但动脉血液气体分析仍然是确定氧化评估的黄金标准.
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