点击反应:食品化学残留检测的范式转变
Fengyu Guo1, Wenhua Jin1, Yanjin Du1
1Department of Nutrition and Health, China Agricultural University, Beijing, China.
Comprehensive reviews in food science and food safety
|December 8, 2025
概括
点击化学提供快速,灵敏的检测食品污染物,如杀虫剂和抗生素. 本综述探讨了基于化学的生物传感器,以改善食品安全分析和现场查.
科学领域:
- 分析化学 分析化学
- 生物传感器技术技术
- 食品安全科学 食品安全科学
背景情况:
- 食品中的化学残留物 (杀虫剂,抗生素,激素) 构成全球健康风险.
- 现有的检测方法 (染色学,免疫试验) 在灵敏度,复杂性和现场应用方面存在局限性.
- 点击化学为快速,特定和超敏感的残留物检测提供了一个有希望的替代方案.
研究的目的:
- 审查点击化学的原理和应用,用于开发食品安全的先进生物传感器.
- 评估最近基于点击化学的传感器设计及其优化策略.
- 为应对挑战,并探索食品污染物分析中点击化学的未来方向.
主要方法:
- 审查点击化学原理,分类和反应特征.
- 将点击化学与生物传感器平台的整合用于增强检测.
- 分析传感器设计策略,包括探头功能化和纳米材料工程.
- 评估先进的传导机制和方法来克服矩阵干扰.
主要成果:
- 点击化学可实现选择性,轻度和模块化反应,用于敏感的分析物检测.
- 基于化学的生物传感器显示出快速,超敏感和现场选食品污染物的潜力.
- 诸如分子印记和人工智能改进等策略解决了诸如矩阵效应和试剂稳定性等挑战.
结论:
- 基于化学的生物传感器代表了食品安全分析的重大进步.
- 未来的工作应该专注于绿色化学,复合,并扩大应用到新出现的污染物.
- 这些创新为可扩展的下一代分析工具铺平了道路,以提高食品安全标准.
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