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Updated: Jan 9, 2026

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors
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Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

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从受体蛋白中提取的富含宏分子光,用于通过差分传感通过敏感药物识别来识别敏感药物

Shiqi Liuye1, Tianhao Shi1, Yang Zhou1

  • 1State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, Collaborative Innovation Center of Chemistry for Energy Materials (iChEM), Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province (IKKEM), College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China.

Analytical chemistry
|December 8, 2025
PubMed
概括

这项研究介绍了一种基于的新型传感器阵列,用于检测合成非法药物. 该阵列在同时识别多种药物方面实现了高准确度和灵敏度,即使在复杂的样本中,如人工尿液.

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Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...
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