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Updated: Jan 9, 2026

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
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向酸途径可以通过重新连接全活性T细胞代谢来缓解移植与宿主疾病

Saeed Daneshmandi1,2, Eun Ko3, Qi Yan1

  • 1Department of Cell Stress Biology, and.

JCI insight
|December 8, 2025
PubMed
概括

酸通路 (PPP) 驱动了T细胞在移植对宿主疾病 (GvHD) 中的增殖. 在PPP中抑制6酸酸脱酶 (6PGD) 酶可以降低GvHD的严重程度,同时保持抗瘤作用.

关键词:
免疫学 免疫学 免疫学在瘤学瘤学.干细胞移植 干细胞移植在T细胞,T细胞.

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