对局部类固醇戒断的在线演讲进行映射:准确性,安全性和支持证据
Joyce J Zhu1, Annabel Hou1, Jillian Baader1
1Department of Dermatology, University of South Florida Morsani College of Medicine, Tampa, USA.
Cureus
|December 8, 2025
概括
局部类固醇戒断 (TSW) 在线讨论揭示了许多个人经历,但缺乏准确,安全的信息. 然而,由医生生成的内容显示出高度的准确性和安全性,强调了需要专家参与TSW话语的必要性.
科学领域:
- 皮肤病学 皮肤病学
- 社交媒体分析 社交媒体分析
- 患者体验研究 研究研究
背景情况:
- 局部类固醇戒断 (TSW) 是局部皮质类固醇戒断的一个公认的不良影响.
- 在线社区广泛讨论TSW,但信息准确性和安全性是令人担忧的.
- 目前,TSW缺乏标准化的诊断标准和研究.
研究的目的:
- 分析关于TSW的社交媒体讨论.
- 了解患者对TSW的看法.
- 评估在线TSW话语的准确性和安全性.
主要方法:
- 在Instagram,TikTok和Reddit上对TSW讨论的内容分析.
- 皮肤病学专业人员对教育和医生生成的内容进行了评分,以准确性,安全性和一致性.
- 对r/eczema.的Reddit帖子进行了情绪分析.
主要成果:
- 大多数在线内容包括个人用户体验.
- 在Instagram和TikTok上的教育内容在准确性和安全性方面得分很低.
- 医生生成的内容在准确性,安全性和一致性方面获得了高评分 (4.25/5).
- 有限证据的非传统治疗方法经常被用户讨论.
- 皮肤科医生讨论的治疗方法,如dupilumab在案例研究中显示出有前途.
结论:
- 不受监管的在线TSW咨询对患者的福祉构成风险.
- 标准化TSW诊断标准是必不可少的.
- 增加皮肤科医生的在线参与对于患者的安全和护理至关重要.
- 迫切需要对TSW管理进行进一步的研究.
相关概念视频
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids
1.5K
Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
1.5K
Drug Dosage Regimen: Overview
4.3K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
4.3K
Pharmacovigilance
1.6K
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
1.6K
COPD: Management Using Bronchodilators and Corticosteroids
705
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
705
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
413
Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2...
413
Drug Administration and Therapy Phases: Overview
1.1K
Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
1.1K


