激烈的响应 利多卡因输液治疗 慢性泛性疼痛 二次性 多重大体
Seung J Lee1,2, Samuel Maccormick1, Kanchana Gattu1
1Anesthesiology, University of Maryland School of Medicine, Baltimore, USA.
Cureus
|December 8, 2025
概括
静脉注射利多卡因输液为患有慢性,难治的 keloid 相关疼痛的患者提供了显著的疼痛缓解. 这种治疗改善了生活质量和功能,为类似的病例提供了潜在的治疗选择.
科学领域:
- 皮肤病学 皮肤病学
- 疼痛管理 疼痛管理
- 药理学 药理学是指药理学的学科.
背景情况:
- 状体是良性纤维扩散性病变,导致慢性疼痛和功能障碍.
- 目前治疗痛的现有治疗方法提供有限的持续缓解.
- 静脉注射利多卡因对 keloid-associated 疼痛的疗效没有得到充分的证据.
研究的目的:
- 评估静脉注射 (IV) 利多卡因输注在治疗与广泛的胆固醇相关的慢性,难以治疗的疼痛方面的有效性.
- 评估IV利多卡因对耐火性 keloid 疼痛患者的生活质量和功能能力的影响.
主要方法:
- 一个45岁的女性的病例报告,在童年水之后,多个大胆体引起了普遍的身体疼痛.
- 审查先前的治疗方法,包括皮质类固醇,各种口服药物,针和局部利多卡因.
- 通过静脉输注利多卡因 (5毫克/千克/小时) 并使用视觉模拟量表 (VAS) 评估疼痛减轻.
主要成果:
- 传统和中度缓解疼痛的治疗只能提供暂时或部分改善 (VAS 8/10).
- 静脉输注利多卡因显著降低疼痛 (VAS 3/10),改善生活质量和功能能力.
- 通过每四个月一次的输液实现了持续的疼痛缓解,没有任何不良的心脏或神经事件.
结论:
- 定期静脉注射利多卡因注射可能是患有慢性 keloid 相关疼痛的患者持续止痛的安全和有效选择.
- 这种方法为与纤维增殖性皮肤病变相关的耐火性疼痛提供了一个新的治疗策略.
- 需要进一步的研究,以探索IV利多卡因在管理 keloid 疼痛综合征中的更广泛应用.
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