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饮食炎症指数和心血管风险和死亡率:更新的系统综述和元分析

Yu Ni¹, Qian Yao², Ting Xu³

¹School of Nursing, Chengdu Medical College, Chengdu, China.

Frontiers in cardiovascular medicine

|December 8, 2025

概括

促炎症饮食,以更高的饮食炎症指数 (DII) 评分来表示,显著增加心血管疾病 (CVD) 发病率和死亡率的风险. 促进抗炎饮食对于减少全球心血管疾病负担至关重要.

科学领域:

营养科学营养科学
心血管健康心血管健康
流行病学流行病学

背景情况:

心血管疾病 (CVD) 是全球主要的死亡原因.
慢性炎症在心血管疾病的发展中起着关键作用.
促炎症饮食可能会通过加剧炎症增加心血管疾病的风险.

研究的目的:

系统地审查和元分析饮食炎症指数 (DII) 与心血管疾病发病率和死亡率之间的关联.
更新有关饮食炎症潜力与心血管结果之间的联系的现有知识.

主要方法:

在多个数据库中进行了全面的文献搜索,直到2025年2月.
包括30项涉及669,205名参与者的队列研究,并对其质量进行了评估.
风险比率 (HR) 和95%置信区间 (CI) 使用元分析技术进行了聚合.

主要成果:

较高的DII分数与心血管疾病发病率 (HR=1.23,95% CI:1.14-1.33) 和死亡率 (HR=1.29,95% CI:1.24-1.35) 的增加有显著相关性.
升高的DII与心肌梗塞风险有显著的积极关联 (HR=1.41).
分层分析揭示了性别特异性风险差异和与糖尿病病史的显著相互作用.

结论:

较高的DII,表明有助于炎症的饮食,与心血管疾病发病率和死亡率的风险更高有关.
这些发现凸显了抗炎饮食模式对公共健康的重要性.
促进抗炎饮食可以帮助减轻心血管疾病的全球负担.

关键词:

心血管疾病心血管疾病饮食炎症指数饮食炎症指数这是一个元分析.死亡率死亡率危险的风险危险的风险更新的系统审查.

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