活体供体肝移植中的超缩小移植:技术和结果
Soumyadip Sain1, Hirak Pahari2, Shikhar Tripathi1
1Department of GI Surgery, Sir Ganga Ram Hospital, New Delhi 110060, India.
World journal of transplantation
|December 8, 2025
概括
超缩小的左侧段 (HRLLS) 和单片段移植 (MSG) 是有效的儿科肝移植在幼儿中. 这些技术实现了高生存率,并减轻了与大型移植相关的并发症.
科学领域:
- 儿科手术 儿科手术
- 移植免疫学 移植免疫学
- 肝病学 肝病学是一种肝病学.
背景情况:
- 儿科肝移植 (LT) 对末期肝病至关重要.
- 移植尺寸不匹配是婴儿 (<10公斤) 的一个主要挑战.
- 较大尺寸的移植有可能导致血管血栓形成和输液不良.
研究的目的:
- 分析在儿科LT中超缩小左侧段 (HRLLS) 和单段移植 (MSG) 的技术和结果.
- 评估小受体的移植修饰策略.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 在PubMed,Scopus和Google Scholar的文献搜索到2025年2月.
- 使用乔安娜·布里格斯研究所批判性评估清单进行质量评估.
主要成果:
- 包括18项关于切片减少技术的研究.
- 高血压低血压低血压低血压低血压和多血压低血压低血压低血压低血压低血压高血压低血压低血压低血压低血压低血压低血压高血压低血压低血压高血压低血压低血压高血压低血压低血压低血压高血压低血压高血压低血压低血压高血压低血压低血压高血压低血压低血压低血压高血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低血压低低
- 并发症 (例如,血栓形成,败血症) 略高但可以接受;移植类型之间没有显著的生存差异.
结论:
- HRLLS和MSG使小接受者能够成功地获得儿科LT.
- 实现与标准移植相美的长期结果.
- 扩大供体库,优化存活率,同时减少并发症.
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