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在儿科肝移植中使用常温机器输液:三个病例报告
Christine S Hwang1,2, Andrew D Shubin1,3, Amal Aqul4
1Division of Surgical Transplantation, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States.
World journal of transplantation
|December 8, 2025
概括
使用OCS肝脏的Normothermic机器输液 (NMP) 是用于儿科肝脏移植 (LT) 的可行技术. 这种方法应用于三个儿科患者,表现出极好的结果,可以优化捐赠者和接受者因素,以获得成功的LT.
科学领域:
- 肝胆道手术是肝胆道的手术.
- 移植医学是一种移植医学.
- 机器 perfusion 技术 机器 perfusion 技术 机器 perfusion 技术 机器 perfusion 技术 机器 perfusion 技术 机器 perfusion 技术 机器 perfusion 技术
背景情况:
- 使用OCS的Normothermic机器输液 (NMP) 肝脏越来越多地用于成年人肝脏移植 (LT).
- 它在儿科LT中的应用较少确立.
- 肝脏已经显示出降低后再输血综合征和早期全移植功能障碍的潜力.
研究的目的:
- 描述使用NMP与OCS肝脏进行儿科肝脏移植的第一个案例系列.
- 评估这项技术在儿科接受者的可行性和结果.
主要方法:
- 三名接受肝移植的儿科患者的病例系列.
- 使用OCS肝脏的Normothermic机器输液 (NMP) 保存肝脏.
- 患者有不同的肝病病因.
主要成果:
- 在所有三个儿科患者中,移植成功.
- 所有患者的临床状况良好,随访时间从7个月到16个月不等.
- 在儿科LT中证明了OCS肝脏的可行性,包括生病的接受者.
结论:
- 使用OCS肝脏进行Normothermic机器输液是儿科肝脏移植的可行和有效策略.
- 这种技术可以优化捐赠者和接受者因素,从而产生出色的结果.
- 它有望改善即使是最严重的儿科LT候选人的结果.
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