墨西哥肝移植的地理差异 墨西哥肝移植的地理差异
Pilar Leal-Leyte1, Natalia Rodriguez-Payan2, Maria P Cote2
1Department of Organ Transplantation, Navy Medical Center, Mexico City 04470, Mexico.
World journal of transplantation
|December 8, 2025
概括
地理差异显著影响墨西哥的肝移植 (LT) 获取. 靠近LT中心的患者有更高的等候名单访问和移植可能性,需要系统修订.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 移植手术 移植手术
- 公共卫生政策 公共卫生政策
背景情况:
- 肝病是墨西哥死亡的主要原因之一.
- 肝移植 (LT) 严重受限,之前没有关于获得平等的报告.
- 对LT接入的地理差异的分析至关重要.
研究的目的:
- 调查墨西哥肝移植 (LT) 获取的地理差异.
- 评估患者位置对LT等候名单和移植率的影响.
主要方法:
- 评估了墨西哥的LT等候名单注册和LT费率 (2014-2023年).
- 计算每百万人口的LT列表 (pmp) 和观察到预期的列表.
- 在高LT活动状态和其他患者之间比较等待列表访问,移植率和死亡率.
主要成果:
- 60.4%的等待名单注册和92.5%的LT发生在高LT活动的国家.
- 高LT活动状态显示显著更高的列表pmp (3.8对1.2) 和LT pmp (2.7对0.7).
- 患有高LT活动状态的患者在上市后移植的可能性增加了1.14倍 (HR 1.14;P=0.009).
结论:
- 在墨西哥的LT访问中存在显著的地理差异.
- 靠近移植中心的位置显著增加了等候名单的访问 (3.2倍) 和LT的可能性 (3.8倍).
- 迫切需要对推系统和资源分配进行审查,以解决地理障碍.
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