儿童和青少年甲状腺癌中枢淋巴结和远程转移的风险因素分析
Ruirui Zhang1, Mengjin Sun1, Siyue Ding1
1Department of Ultrasound, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China.
Frontiers in oncology
|December 8, 2025
概括
在儿科甲状腺癌中,性别和远程转移 (DM) 是中枢淋巴结转移 (MLNM) 的独立风险因素. 损伤形态和中央转移性淋巴结比率 (CCLNR) 独立预测DM风险.
科学领域:
- 儿科瘤学 儿科瘤学
- 内分泌学 在内分泌学.
- 癌症研究 癌症研究
背景情况:
- 儿童和青少年的甲状腺癌面临着独特的挑战.
- 了解转移风险因素对于有效的治疗计划至关重要.
研究的目的:
- 在儿童和青少年甲状腺癌患者中识别中枢淋巴结转移 (MLNM) 和远程转移 (DM) 的风险因素.
- 评估中央转移性淋巴结比率 (CCLNR) 的预测值.
主要方法:
- 67名儿童和青少年甲状腺癌患者 (2015-2022) 的回顾性分析.
- 对临床,病理和手术前超声波数据的统计分析.
- 进行了单变量和多变量回归分析.
主要成果:
- MLNM发生在20.9%的患者中,DM发生在31.3%的患者中.
- 性别和DM是独立的MLNM风险因素.
- 损伤形态和CCLNR是独立的DM风险因素.
结论:
- 更高的CCLNR与增加的MLNM和DM风险相关.
- 一个CCLNR>0.79表明在这个人群中MLNM和DM的高风险.
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