术前2小时碳水化合物负荷对接受选择性手术的儿科患者的影响:一项随机对照研究
Wafaa Madhy Atia Abdelwahed1, Wafaa Mohamed Abdelelsalam2, Ola Ahmed Taha3
1Anesthesiology, Surgical Intensive Care and Pain Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt, tanta.edu.eg.
Anesthesiology research and practice
|December 8, 2025
概括
在接受手术的儿童中,手术前的碳水化合物负载改善了新陈代谢标志物,与标准禁食相比,减少了炎症. 这种方法提高了患者的舒适度和家长的满意度,为儿科手术患者提供了一个安全的替代方案.
科学领域:
- 儿科麻醉学 儿科麻醉学
- 手术营养是指手术营养.
- 代谢医学是一种代谢医学.
背景情况:
- 在儿科患者中,长时间的手术前禁食会导致代谢障碍和不适.
- 标准的禁食协议可能会对接受手术的儿童的生理标志物产生负面影响.
研究的目的:
- 评估不同手术前碳水化合物 (CHO) 负载在接受选择性手术的儿科患者的全身影响.
- 为了比较果汁,无水葡萄糖和水对代谢和炎症标志物的影响.
主要方法:
- 一个随机的单盲受控试验,涉及90名计划接受选择性手术的儿童 (5-10岁).
- 在手术前2小时,三组接受了果汁,无水葡萄糖或水,并遵循标准的禁食指南.
- 评估炎症标志物,胰岛素抵抗 (IR),随机血糖和父母的满意度.
主要成果:
- 与水相比,碳水化合物负载 (果汁和葡萄糖) 显著降低了炎症标志物.
- 胰岛素耐药性标记物在碳水化合物加载时更好地保存,尽管血糖水平显示过渡性变化.
- 在接受碳水化合物负载与水相比的组中,父母的满意度显著更高.
结论:
- 手术前的碳水化合物加重是儿科选择性手术中标准禁食的安全有效替代方案.
- CHO加载改善了新陈代谢,减少了炎症反应,提高了父母的满意度.
- 这一策略优化了儿科手术患者在术后期的患者结果和舒适度.
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