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Updated: Jan 9, 2026

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具有异常DNA聚合酶活性的POLQ变体可以防止紫外线诱导的细胞死亡

Steven Weicksel, Corey Thomas, Ethan Hall

    bioRxiv : the preprint server for biology
    |December 8, 2025
    PubMed
    概括

    变异型DNA聚合酶Q (POLQ) 在修复循环butan胺二次体 (CPD) 中显示效率降低,但可以保护细胞免受紫外线辐射诱导的死亡,这表明它在癌症中起着双重作用.

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