多重主性中枢神经系统淋巴瘤在腹腔系统和腹腔间:一个病例报告
Qing Ouyang1, Bing Sun1, Haodong Sun1
1Department of Neurosurgery, General Hospital of The Western Theater Command, Chengdu, Sichuan 610083, P.R. China.
Oncology letters
|December 8, 2025
概括
多重原发性中枢神经系统淋巴瘤 (PCNSL) 很少见,特别是在心室系统内. 这项研究详细介绍了一种罕见的多重PCNSL病例,强调手术切除和化疗是有效的治疗方法.
科学领域:
- 神经瘤学神经瘤学
- 神经病理学神经病理学
- 神经外科 神经外科
背景情况:
- 多重原发性中枢神经系统淋巴瘤 (PCNSL) 是一种不常见的诊断.
- PCNSL的静脉内干涉特别罕见,这给诊断和治疗带来了挑战.
研究的目的:
- 描述一种罕见的多重PCNSL病例,涉及心室系统,脑髓和骨架间.
- 在这个解剖分布中审查PCNSL的文献.
- 讨论心室系统中PCNSL最佳管理策略.
主要方法:
- 一个67岁的男性患有恶心,吐和静止性低血压的症状.
- 诊断工作包括磁共振成像 (MRI),揭示了多个增强性损伤.
- 第四心室病变的手术切除,随后通过组织病理学确认扩散大B细胞淋巴瘤.
主要成果:
- 该患者出现了与多个PCNSL病变相关的神经症状.
- 第四心室病变的最大安全切除提供了症状缓解.
- 组织病理学证实了扩散性大B细胞淋巴瘤,这是PCNSL的常见亚型.
结论:
- 腹腔系统,脑髓和骨干间中的多重PCNSL可能来自胆管并通过脑脊液传播.
- 手术切除与化疗相结合,代表了PCNSL目前的护理标准.
- 在第四室内对PCNSL进行最大限度的安全切除可以减轻阻塞性水风险.
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