自闭症特征和酒精消费通过青春期和年轻成年期
Stephanie Page1,2, Kayleigh E Easey1,3, Felicity Sedgewick4
1MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom, BS1 5DS.
medRxiv : the preprint server for health sciences
|December 8, 2025
概括
具有较高自闭症特征的自闭症成年人饮酒量较少. 然而,更大的社交沟通差异与重饮者的酒精消费增加有关.
科学领域:
- 神经发育障碍 神经发育障碍
- 成研究研究成研究
- 公共卫生 公共卫生
背景情况:
- 新兴研究表明,自闭症成年人的危险酒精消费率更高.
- 目前,对于自闭症成年人危险饮酒的支持服务不足.
- 了解自闭症特征与酒精使用之间的纵向关系对于及时干预至关重要.
研究的目的:
- 调查自闭症特征与酒精消费模式之间的纵向关联.
- 检查自闭症个体对酒精使用的表型和遗传影响.
主要方法:
- 利用了来自阿文长度研究的父母和孩子 (ALSPAC) 的数据.
- 使用广泛的自闭症表型测量,社会沟通障碍检查清单和自闭症多基因评分来测量自闭症特征.
- 在17岁至28岁之间的五个时间点中评估了酒精消费,使用多级块状线性线条分析.
主要成果:
- 对自闭症的遗传责任对酒精消费的影响很小.
- 在大多数测量量量中,更高的自闭症特征与更低的酒精消费有关.
- 更大的社交沟通差异与更高的酒精消费相关,特别是在第90百分位 (重度饮酒).
结论:
- 社会沟通差异与大量饮酒的自闭症成年人增加的酒精摄入量有关.
- 自闭症特征与饮酒之间的关联是复杂的,并取决于测量方法.
- 需要进一步的研究,以了解这些协会在不同的自闭症子群体和饮酒模式.
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