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Updated: Jan 9, 2026

Generation of High Quality Chromatin Immunoprecipitation DNA Template for High-throughput Sequencing ChIP-seq
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Generation of High Quality Chromatin Immunoprecipitation DNA Template for High-throughput Sequencing ChIP-seq

Published on: April 19, 2013

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通过结合罕见,低频率和特定人群的变异来改善2型糖尿病多基因风险评分

Katie Taylor1, Alicia Huerta-Chagoya1,2,3, Xiaoyu Wang4,5

  • 1Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, 2142, USA.

medRxiv : the preprint server for health sciences
|December 8, 2025
PubMed
概括

在多基因风险评分 (PRSs) 中纳入罕见和特定人群的变异可显著改善2型糖尿病 (T2D) 的预测,特别是在罕见变异携带者身上. 像CTSLEB这样的新方法在不同人群中显示出更高的准确性.

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