在损害控制手术中手术培养的微生物学概况:临床含义和预测因素
Hyunseok Jang1, Younggoun Jo1, Yunchul Park1
1Division of Trauma, Department of Surgery, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea.
Surgical infections
|December 8, 2025
概括
在损伤控制手术 (DCS) 中的手术培养预测感染并发症,但不预测死亡率. 阳性培养可以识别患有手术部位感染和的风险较高的患者,有助于感染监测.
科学领域:
- 创伤外科 手术 创伤外科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 损伤控制手术 (DCS) 对于管理腹部创伤至关重要.
- 识别DCS患者的感染风险对于改善结果至关重要.
- 微生物监测有助于向治疗和预防感染.
研究的目的:
- 在接受DCS的患者中研究手术培养的微生物特征.
- 评估阳性培养和临床结果之间的关联,包括感染并发症和死亡率.
- 确定培养在此患者群体中感染风险分层的有用性.
主要方法:
- 这是一项对122名因腹部创伤而接受DCS的患者的回顾性观察性研究.
- 来自手术,腹部和伤口培养的微生物数据的分析.
- 培养阳性和培养负组之间的临床特征和术后感染并发症的比较.
- 多变量后勤回归用于识别感染并发症的独立预测因素.
主要成果:
- 在58.2%的患者中,培养为阳性.
- 阳性培养与更高的手术部位感染率,腹内,肺炎显著相关.
- 阳性培养 (OR: 3.49) 和高红细胞输血量 (OR: 4.29) 是传染性并发症的独立预测因素.
- 培养阳性与死亡率没有关联 (p = 0.982).
结论:
- 在DCS中获得的手术培养提供了独立的感染风险分层.
- 阳性培养物可以预测感染并发症,支持它们在感染监测中的使用.
- 微生物特征因解剖部位而异,这表明需要针对特定部位的抗菌策略.
- 对于接受DCS的患者来说,例行培养采集可能是有益的.
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