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Updated: Jan 9, 2026

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布鲁萨托尔通过调节UBE3A-LCN2-介导的铁和炎症轴,在性结肠炎中发挥治疗作用

Xingzhuo Guan1, Xiaohui Guan1, Zhiping Yang1

  • 1Department of Gastroenterology, Affiliated Hospital of Beihua University, Jilin, Jilin Province, China.

Chemical biology & drug design
|December 8, 2025
PubMed
概括

布鲁萨托尔 (BR) 通过调高UBE3A和降低LCN2来治疗性结肠炎 (UC),减少炎症和细胞损伤. 这项研究澄清了BR BR.

关键词:
在 LCN2 中, LCN2 是这就是UBE3A.布鲁萨托尔 (brusatol) 是一种类型的药.铁性化 (ferroptosis) 是一种无处不在的化性结肠炎是一种

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