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Updated: Jan 9, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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瘤源的p53N236S通过调节DREAM/MMB和下游端粒DNA复制通路来平衡衰老和瘤发生

Qianqian Wang1, Haili Li2, Quan Zheng3

  • 1Department of Pathophysiology, School of Basic Medicine, Guizhou Medical University, Guiyang 561113, China.

Journal of molecular cell biology
|December 8, 2025
PubMed
概括

一种特定的p53突变 (p53S) 通过调节DNA修复途径并解决复制压力,在韦纳综合征 (WS) 小鼠中挽救了过早衰老,提供了一种新的长寿策略.

关键词:
复制DNA复制DNA复制DNA复制在DREAM/MMB路径上.维纳综合征是什么意思 维纳综合征是什么意思这就是p53突变.端粒是什么意思 端粒是什么意思

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