Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Increasing power and robustness in screening trials by testing stored specimens in the control arm.

BMC medical research methodology·2026
Same author

Comparing approaches to designing and accelerating evaluation of multicancer early detection tests.

Journal of the National Cancer Institute·2026
Same author

Adjusting for non-compliance and contamination with a more plausible assumption.

Journal of medical screening·2026
Same author

Framework to Select Multi-Cancer Detection Assays in the National Cancer Institute's Vanguard Study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology·2025
Same author

The Role of the Extracellular Matrix in Cancer Prevention.

Cancers·2025
Same author

Testing stored control-arm specimens could dramatically increase statistical power yet reduce costs in cancer screening trials.

Journal of the National Cancer Institute·2024
Same journal

Cost-benefit analysis of an organized community-based multi-cancer screening program in Bangladesh.

Journal of medical screening·2026
Same journal

Response to: Adjusting for non-compliance and contamination with a more plausible assumption.

Journal of medical screening·2026
Same journal

Response to Takahashi regarding Bestwick and Wald: Mischaracterisation of evidence in prostate cancer screening.

Journal of medical screening·2026
Same journal

No-cost envelope modification improves fecal immunochemical test laboratory acceptance in a US Veterans Affairs colorectal cancer screening trial.

Journal of medical screening·2026
Same journal

Prostate cancer screening: The level of the evidence hierarchy.

Journal of medical screening·2026
Same journal

Prediction model to prioritize colorectal cancer screening with visual colonoscopy.

Journal of medical screening·2026
查看所有相关文章

相关实验视频

Updated: Jan 9, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K

有效的存储样本设计用于评估多种查技术:应用于多种癌症检测测试.

Stuart G Baker1, Hormuzd A Katki2

  • 1Independent Researcher, Columbia, MD, USA.

Journal of medical screening
|December 8, 2025
PubMed
概括
此摘要是机器生成的。

与标准方法相比,高效的存储样本 (ESS) 设计显著减少了用于评估多重多种癌症检测 (MCD) 测试的样本大小. 这种新的方法提高了癌症查研究的效率.

关键词:
预期的效果预期的效果液体活检活检液体活检多种癌症检测 (MCD) 试验一个随机的小径.

更多相关视频

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

12.2K
Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
08:58

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

565

相关实验视频

Last Updated: Jan 9, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

12.2K
Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
08:58

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

565

科学领域:

  • 在瘤学瘤学.
  • 生物统计学 生物统计学
  • 医学诊断 医学诊断 医学诊断

背景情况:

  • 多种癌症检测 (MCD) 试验旨在通过使用血液样本查多种癌症来降低癌症死亡率.
  • 开发高效的研究设计对于评估目前正在开发的众多MCD测试至关重要.
  • 评估多个MCD测试的传统设计可能是样本大小密集的.

研究的目的:

  • 引入和评估一种新的研究设计,即高效储存样本 (ESS) 设计,用于评估多重多重癌症检测 (MCD) 试验.
  • 将ESS设计的样本大小效率与标准存储样本 (SSS) 设计进行比较.
  • 在ESS框架内开发一种简单的分析方法来评估单个MCD测试.

主要方法:

  • 高效的存储样本 (ESS) 设计将参与者随机分配到延迟的MCD测试或单一组接受多个立即的MCD测试.
  • 标准存储样本 (SSS) 设计涉及将参与者随机分配到延迟测试的对照组或立即测试的多组.
  • 两种设计都使用存储的标本,但ESS设计将即时测试整合到一个臂.

主要成果:

  • 根据ESS设计和SSS设计,每个随机化组的样本大小相同.
  • 为了评估*k*的MCD测试,ESS设计只需要2个随机化组,而SSS设计需要*k*+1个相同大小的组.
  • 这种整合大大减少了ESS设计所需的总体样本大小.

结论:

  • 与SSS设计相比,ESS设计在评估多个MCD测试时,在样本大小效率方面提供了显著的改进.
  • 这种提高效率可以实现,而不需要额外的统计假设.
  • 欧洲癌症检测系统 (ESS) 的设计代表了一种更有效利用资源的方法,以推进多种癌症检测试验研究.