相关实验视频

Updated: May 12, 2026

Engineering and Evolution of Synthetic Adeno-Associated Virus AAV Gene Therapy Vectors via DNA Family Shuffling
21:55

Engineering and Evolution of Synthetic Adeno-Associated Virus AAV Gene Therapy Vectors via DNA Family Shuffling

Published on: April 2, 2012

29.1K

人工智能驱动的转移学习和经典分子动力学,用于战略性治疗重定位和针对水病毒DNA聚合酶的抗病毒的合理设计

Leona Dcunha1, Sonet Daniel Thomas1, Levin John2

  • 1Center for Integrative Omics Data Science, Yenepoya (Deemed to be University), Mangalore, Karnataka, 575018, India.

Computers in biology and medicine
|December 8, 2025
PubMed
概括

研究人员对FDA批准的药物进行了选,并设计了用于对抗水病毒 (MPXV) 的新. 帕罗莫米辛和一种合成,CFC,对MPXVDNA聚合酶表现出有前途的抗病毒活性,提供了潜在的新疗法.

关键词:
计算病毒学计算病毒学.深度学习的药理学模型.药物重新定位是药物重新定位.以知识为导向的基生成.麻疹病毒的病毒.合成的合成.

更多相关视频

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit22:10

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit

Published on: June 28, 2013

13.6K
Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors10:29

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

Published on: May 9, 2025

2.1K

相关概念视频

Inhibitors of Viral Protein Synthesis01:30

Inhibitors of Viral Protein Synthesis

Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...