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Updated: Jan 9, 2026

Author Spotlight: Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos
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控制RhoA活性和相关的突触效应的机制是由DISC1类似脚手架的蛋白质控制的

Kathryn J Bjornson1, Michael E Cahill1

  • 1Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, 53706, USA.

Biological psychiatry
|December 8, 2025
PubMed
概括

DISC1蛋白抑制PDZ-RhoGEF过度激活RhoA,防止树突性脊柱损失. 这种机制对于维持神经功能和理解双相情绪障碍病理生理学至关重要.

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