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大肠直肠癌中的乳化:从机制到临床应用

Peng Chen¹, Yu-Hong Gao², Shu-Xian Xie¹

¹Department of Surgical Oncology, Fuzhou Hospital of Traditional Chinese Medicine, Fuzhou, Fujian, China.

Biochemical pharmacology

|December 8, 2025

概括

乳化是一种表观遗传修饰,越来越多地与结直肠癌 (CRC) 的发展和进展有关. 这篇评论探讨了乳酸化.

科学领域:

表观遗传学在表观遗传学中,表观遗传学是指表观遗传学.
分子生物学分子生物学
在瘤学瘤学.

背景情况:

乳化是一种新兴的表观遗传修饰,调节蛋白质功能和基因表达.
它涉及乳酸盐对氨酸残留物的动态修饰.
乳糖化在癌症特征中起着至关重要的作用,如代谢重编程,免疫逃避,转移和耐药性.

研究的目的:

在结直肠癌 (CRC) 中系统地审查乳化分子机制和生物功能.
总结一下当前对乳化在癌症中的作用的理解.
讨论针对癌症的向乳化疗法的进展和未来方向.

主要方法:

对乳糖和CRC现有研究的文献综述.
分子机制和生物功能的系统总结.
分析当前的研究趋势和治疗策略.

主要成果:

乳糖化与CRC的发生和发展密切相关.
它影响关键的癌症过程,包括代谢重编程和免疫逃避.
在CRC中乳化研究仍然有限,但显示出显著的潜力.

结论:

乳化是CRC病变发生的一个关键因素.
向乳化疗法为CRC治疗提供了一个有前途的途径.
需要进一步的研究,以充分阐明乳酸化在CRC中的作用和治疗潜力.

关键词:

结肠直肠癌是一种癌症.药物耐药性药物耐药性药物耐药性在表观遗传学上,表观遗传学是表观遗传学.乳母乳化乳母乳化乳母乳化代谢重编程是一种代谢重编程.

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