与其他内镜方法相比,内镜超声波导向卷轴加注射用于治疗胃的治疗方法:系统性审查和元分析
Zinat Mohammadpour1, Maria Castrejon Moreno1, Bobak Moazzami2
1College of Medicine and Dentistry, James Cook University, Cairns, Queensland, Australia.
Journal of gastroenterology and hepatology
|December 8, 2025
概括
与其他内镜方法相比,内镜超声波 (EUS) 引导的线圈和粘合剂注射是一种更有效和更安全的胃静脉治疗方法. 这种方法减少了再干预和再出血的风险,提高了GV消灭率.
科学领域:
- 胃肠病学 胃肠病学
- 干预性内镜检查是干预性的内镜检查.
- 肝病学 肝病学是一种肝病学.
背景情况:
- 胃静脉 (GV) 是门高血压的严重并发症,与高出血风险相关.
- 目前的内镜治疗方法,如粘合剂注射和内镜超声波 (EUS) 导向疗法,都有局限性.
- 通过EUS引导的线圈和粘合剂注入为管理GV提供了一个有希望的替代方案.
研究的目的:
- 为了比较EUS导向线圈和注射的疗效和安全性,与其他内镜模式用于胃静脉的管理.
- 评估结果,如重新干预率,GV消灭率,死亡率和不良事件.
主要方法:
- 在五个数据库中进行了系统的文献搜索,截至2024年10月.
- 使用随机效应模型汇集数据,计算95%置信区间 (CI) 的风险比率 (RR).
- 评估了偏见风险和证据确定性,并进行了子组和敏感性分析.
主要成果:
- 分析了9项涉及579名患者的研究.
- 在EUS线圈和粘合剂中,重新干预风险较低 (RR=0.32) 和GV消灭率较高 (RR=1.18).
- 治疗显示不良事件的总体风险较低 (RR=0.55),包括减少复出血 (RR=0.36),死亡率没有显著差异.
结论:
- 与其他内镜方法相比,EUS引导的线圈和粘合剂注射在治疗胃静脉的有效性和安全性上是优越的.
- 目前的证据虽然有希望,但在质量和确定性方面存在局限性.
- 需要进一步的精心设计的研究来确认长期结果和巩固证据.
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