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Gyula Pálfy1, Johannes Schmoll1, Maria E Pérez1

  • 1Department of Biology, Institute of Biochemistry, ETH Zurich, 8093 Zurich, Switzerland.

Journal of the American Chemical Society
|December 8, 2025
PubMed
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Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
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